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Description
Conditions of infection and inflammation, specifically high levels of IL-6, tend to increase the expression of hepcidin, which then degrades FPN1
Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al
Science 358 , eaal5081 (2017)
All animal experiments undertaken in this study were conducted with the approval of the UK Home Office and the MRC Centre Ethical Review Committee
The combination has not been formally tested in any published clinical trial as of May 2026
Some find it particularly helpful when trying to transition to a lower-carb diet, noting that it helps take the edge off sugar withdrawals
