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Clinical Research Findings In a comprehensive safety analysis published in 2013, researchers evaluated data from six randomized controlled trials spanning five years and involving approximately 900 adult participants

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Neither trial showed primary-endpoint benefit

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& Zechner, R

Freshwater : hypervolemia (in animal models only, not humans, so no clinical relevance) Saltwater : hypovolemia with hypernatremia (in animal models only, not humans, so no clinical relevance) References Auerbachs Wilderness Medicine, 7th Edition, Paul S
