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Circul una polmica sobre el metabolito TMAO (asociado a dosis muy altas), pero los estudios recientes indican que este efecto es negligible a dosis estndar

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Proteine coinvolte nel ciclo della carnitina [modifica | modifica wikitesto] CPT I : carnitina-palmitoil-transferasi I, presente sulla parte esterna della membrana mitocondriale esterna, catalizza il trasferimento di gruppi acile dall'acil-CoA alla carnitina, producendo acil-carnitina

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Furthermore, unabsorbed carnitine is metabolized by gut bacteria into trimethylamine (TMA), which is converted to trimethylamine-N-oxide (TMAO) in the livera metabolite linked to increased cardiovascular risk [4] [9]