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Detoxification of electrophilic compounds by glutathione S-transferase catalysis: Determinants of individual response to chemical carcinogens and chemotherapeutic drugs

[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., Heninger G.R., Bowers M.B., Jr., Charney D.S

In addition, GPx-1 / mice are more susceptible to target tissue damage, such as liver parenchymal cell death, in acute models of inflammatory injury (185)

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Scientists conduct scientific research and analysis in laboratories to observe the effects of these peptides, and responses can vary based on individual biochemistry, age, and weight