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Generally, it is difficult to deplete DHA from the neural membranes of adult mammals even with a DHA low diet, presumably because of preferential uptake of DHA into the brain to support the basal turnover

Johnson JA, Johnson DA, Kraft AD et al (2008) The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

Accordingly, enhancement of astrocytic glycogenolysis improved the outcome from ischemic stroke in vivo as well as increased the survival of neurons in astrocyte-neuron co-cultures exposed to OGD in vitro 57

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

J., De Groot, M

The process of DNA methylation is driven by DNA methyltransferases (DNMTs), which have the ability to transfer a methyl group from S -adenosyl- L -methionine to a DNA basecytosine [52]