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Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A et al

Eshleman AJ, Henningsen RA, Neve KA, Janowsky A (1994)

For instance, in preclinical models, long-term ketamine exposure increases the expression of GABA receptor subunits in the prefrontal cortex while simultaneously reducing glutamate receptor subunits, impairing synaptic signaling and cognitive function ( Ketamine also downregulates brain-derived neurotrophic factor, particularly in the hippocampus, exacerbating deficits in synaptic plasticity and cognitive functions

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Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples

J Clin Psychopharmacol