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PubMed overview on GHK and tissue remodeling
(2020) reported the induction of chondrocyte apoptosis through the upregulation of TNF- (Yang et al., 2021)
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Reduced glutathione: a radioprotector or a modulator of DNA-repair activity
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After that Nrf2 is stabilized and translocate from the cytoplasm to the nucleus via bipartite nuclear localization signal where it then transactivates expression of detoxification enzymes, reducing molecules, antioxidant enzymes, and Nrf2 itself [97]
