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Description
As shown in Figure 2, as the rate-limiting step in the synthesis of fatty acids, acetyl-CoA reacts with bicarbonate and ATP to form malonyl-CoA, which is catalyzed by acetyl-CoA carboxylase (ACC/POD-2)
There's just a fraction of the desired amount delivered in each pump
However, on a glucose-free diet accumulation of glycogen does not compromise their lifespan (Figs 6a and 7a)
Science (80-.) 300 , 11421145 (2003)
Wortmann et al., 2013
Hanson, diagnosed with FA in 2006, recently graduated from the University of Central Florida and works as a high school math teacher
