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Immunosenescence is associated with dysregulated signaling pathways (e.g., overactivation of the NF-B signaling pathway and downregulation of the melatonin signaling pathway) and abnormal immune cell responses with functional alterations and phenotypic shifts

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It plays a vital role in protecting cells from oxidative damage and supporting detoxification pathways.

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fumigatus significantly reduced resistance to elevated H2O2 and menadione, respectively, impaired gliotoxin production and resulted in attenuated conidiation

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