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Chem Res Toxicol 13:363372

In the interim analysis it was observed that in individuals who were anti-CCP positive but without inflammatory arthritis at baseline, one year of HCQ was not superior to placebo in preventing or delaying the development of inflammatory arthritis, and the classification of individuals as having RA at 3 years (probabilities of RA development were 34% in the HCQ arm and 36% in the placebo

Fortier and Matte, 2006)

Liu T., Shang J., and Chen Q., Superoxide Dismutases in Immune Regulation and Infectious Diseases, Antioxidants 14, no

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLC2 signaling axis in mice J