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While early detection of colorectal cancer is vital, the functional medicine approach focuses on prevention

Khan, R

doi: 10.1083/jcb.110.2.327

[DOI] [PubMed] [Google Scholar] Redman LM, de Jonge L, Fang X, Gamlin B, Recker D, Greenway FL, Smith SR, Ravussin E

Department of Agriculture , every 100 grams of durian contains 147 calories, 5 grams of total fat, 2 mg of sodium, 436 mg of potassium, 27 grams of carbohydrates, 1.5 grams of protein

Studies finding protective effects against cancer: A meta-analysis found that two copies of the C677T variant (AA genotype) decrease the risk of colon cancer by about 20%![ref] Another meta-analysis found that two copies of the C677T variant (AA genotype) were protective against prostate cancer .[ref] The MTHFR C677T variant decreases the relative risk of retinoblastoma and oral squamous cell cancer.[ref][ref] Two copies of the C677T variant (AA genotype) are protective against gastric cancer.[ref] However, for someone who has cancer, the MTHFR C677T variant is associated with poorer outcomes.[ref] The MTHFR A1298C variant (GG or GT) is associated with a decreased risk of hypothyroidism .[ref] The flip side: Folate can also help protect against cancerous mutations in the first place