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The separation provides clearer attribution if any unexpected effects occur

doi: 10.3389/fmolb.2021.747629
Mechanisms of overcoming intrinsic resistance to gemcitabine in pancreatic ductal adenocarcinoma through the redox modulation

However, the exact origins of ROS and the mechanisms by which they damage nitrergic neurotransmission in age-related ED remain unidentified

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Early studies have demonstrated that erythrocytes possess caspase-3 and caspase-8 and can die via an apoptotic-like cell death triggered by Ca 2+ ionophores