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Description
This age-related NAD+ depletion impairs mitochondrial energy production, reduces SIRT1 activity, compromises DNA repair mechanisms, and accelerates cellular senescence

Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H

The difference between clinical and practical dosing Clinical trials operated under controlled conditions that do not reflect real-world use

Importantly, preclinical studies showed that weight reduction occurred particularly in abdominal adipose tissue, the visceral fat depot most strongly associated with metabolic health risks

(PubMed) Marti-Carvajal AJ, Sola I, Lathyris D, Dayer M

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