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Proof of principle for this approach was obtained in a mouse model of breast cancer where autotaxin inhibition decreased ARE activation and the consequent expression of anti-oxidant proteins and MDRT 49

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V., Exploiting BBB Disruption for the Delivery of Nanocarriers to the Diseased CNS, Current Opinion in Biotechnology 60 (2019): 146152

Within this initiative, a standardized protocol is employed for the collection and analysis of pancreatic tissue from donors with normoglycemia, prediabetes, and overt T2D