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17 , e3000284 (2019)

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Several types of kidney parenchymal cells seem to express a variety of immune molecules with a distinct topographic distribution, which may reflect the exposure of these cells to different pathogenic threats or microenvironments

demonstrated that oxidative stress, mediated by ROS, plays a crucial role in depression induction, and Nrf2 activation can mitigate oxidative stress by simultaneously regulating multiple potential mechanisms, including autophagy and ferroptosis (ZUO et al., 2022)

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10 Conclusions and future perspectives In conclusion, studying the mechanisms of comorbidity through the perspective of ferroptosis is essential, with GPX4 and Nrf2 being highlighted as critical targets