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Their redox activity is fundamental to maintaining oxidative homeostasis, with GPX4 standing out for its ability to eliminate lipid peroxides and prevent membrane damage

The disease is characterized by infiltration and accumulation of immunoglobulin-secreting neoplastic plasma cells in the bone marrow and, as a result, increased serum or urine monoclonal paraprotein levels

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The final step in the synthesis of glutathione is the linkage of the dipeptide gamma-glutamyl-cysteine with glycine by the action of glutathione synthetase

COVID-19 primarily affects the respiratory tract and can progress to respiratory compromise, severe acute respiratory distress syndrome (ARDS) and death 1,2

Under normal conditions, the molar GSH:GSSG ratio is around 100:1