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Comparison of Fos induced in rat brain by GLP-1 and amylin

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We next examined late endosomes that fuse to lysosomes to digest GLP-1R and other proteins into amino acids and to synthesize new protein

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It will be important to determine which brain GLP-1 receptors are activated by GLP-1 originating in gut enteroendocrine cells, and which by GLP-1 originating from brainstem neurons

Some GLP-1 medications are approved for certain adolescents with obesity, but microdosing and weight loss strategies in teens are not standard care