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How it works Oxidative stress occurs when there is an imbalance between the production of free radicals and the bodys ability to fight them off

-Glutamylcysteine ligase expression is subject to regulation by Nrf2, a transcription factor that regulates a wide array of antioxidant responsive element (ARE)-driven genes in various cell types, and thus plays a central role in cellular antioxidant defenses (Jaiswal, 2004

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