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To bridge this gap, 3D human oligocortical organoids derived from patient-specific NSCs, OPCs, astrocytes or microglia have been proposed to study demyelination, axonal injury and remyelination failure in a genetically and clinically relevant context 198

Cyanocobalamin is a form of vitamin B12 used to treat or prevent B12 deficiency, which can result from dietary limitations, certain types of anemia, pregnancy, gastrointestinal disorders, or other medical conditions

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