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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Haarhaus M, Gilham D, Kulikowski E, Magnusson P, Kalantar-Zadeh K

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We propose that NADPH and GSSG convey TCA cycle status: decreasing the availability of acetyl-CoAeither from lipid or carbohydrate catabolismdampens NADPH production and disfavors glutathione reduction, with the increased GSSG ultimately rendering the ER lumen more oxidizing and protecting ER homeostasis
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