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Description
A clinical study following people with CF on elexacaftor/tezacaftor/ivacaftor (ETI) for 6 months found a significant reduction in antibiotic use by the end of the studysuggesting a lower prevalence of bacterial-induced exacerbations (Nichols et al., 2022)

Individuals with bone marrow disorders 10 , 11

Nolting, H

The BNF recently (2019) changed its guidance for the frequency of injections of hydroxocobalamin: Every 2 months in patients who have neurological symptoms Every 2 or 3 months when there are no neurological symptoms

Empirical evidence indicates that vitrified mouse oocytes at the germinal vesicle (GV) and metaphase II (MII) stages exhibit a significant reduction in MMP, leading to mitochondrial dysfunction (47)

Gastroenterologists focus on both helping their patients into remission, which is the absence of symptoms, and then maintaining remission or preventing flare-ups
