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LINC00160 mediates chemoresistance in breast cancer by recruiting CEBPB to activate TFF3 transcription, with its knockdown suppressing drug resistance, metastasis, and tumor growth in paclitaxel/doxorubicin-resistant cells and xenograft models, correlating with poor clinical chemotherapy response [104]

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However, there is currently no specific scientific research confirming a synergistic effect between these two compounds

Appetite suppression is the third variable

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