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Al bloquear el sitio activo de la enzima de forma permeable a membrana, 5-Amino-1MQ reduce la produccin de 1-MNA y preserva la nicotinamida disponible, lo que en modelos experimentales se asocia con restauracin de los niveles intracelulares de NAD+ y SAM

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In a separate letter published in the NEJM, U.S

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