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Successfully inhibiting ferroptosis exclusively in healthy tissues will be the most important goal for drug development
The relevance of impaired selenium metabolism to the onset of KBD was further validated using a mouse genetic deletion model

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However, in our opinion, only those states correlating with low levels of IGF-I may benefit from a real replacement therapy, thus avoiding potential adverse effects [49]

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Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis
