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Description
New vectors for epitope tagging and gene disruption in Schizosaccharomyces pombe

In the oxidized state, PDI acts as a disulfide donor

Statistical significance can be achieved with small samples when effect sizes are large, but generalisability remains uncertain

According to the results from in vitro and in vivo studies, tanshinone IIA pretreatment protects the liver from APAP-induced liver injury by activating Nrf2 and increasing the mRNA and protein levels of the Nrf2 target genes glutamate-cysteine ligase catalytic subunit (GCLC), NQO1, and HO-1 (Wang et al., 2016)

doi: 10.1158/1055-9965.EPI-03-0012 122 MengL-QYangF-YWangM-SShiB-KChenD-XChenDet al

Through ROS-mediated phosphorylation of IB kinase, NF-B is released from its inhibitor and translocates to the nucleus, where it induces transcription of pro-inflammatory cytokines, chemokines, adhesion molecules, and iNOS itself
