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Published 2016 Nov 4

Form: Capsules (for research use only) Target: Nicotinamide N-methyltransferase (NNMT) inhibitor Suggested Application: Preclinical or in vitro metabolic studies Storage: Preserve in a cool, dry environment away from direct light 1

The gold nanoparticle solution is approximately 5.6 in pH and so the GSH binds to the gold nanoparticles in two places via the SH functional group from the glutamate moiety and the COO- functional group 55, 56

Avoid these during the first week: Retinoids and retinol-based products AHAs (glycolic acid, lactic acid) and BHAs (salicylic acid) Alcohol-based toners and astringents Benzoyl peroxide treatments Vitamin C in high concentrations (can sting on fresh micro-channels) Stick with gentle hydrators, copper peptides, and barrier-supporting ingredients instead

doi: 10.7554/eLife.57028 19 GoldsteinG

Concurrently, it undermines the hosts GPX4 defenses by mobilizing lysosomal chaperon-mediated autophagy (CMA) 14