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II Patients who had an ostomy or colectomy, or discontinued study agent due to lack of therapeutic effect or due to an adverse event of worsening of UC after Week 44 and prior to the designated visit, were considered not to be in symptomatic remission

Acknowledgments The authors sincerely appreciate Kobilka Institute of Innovative Drug Discovery

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A few key approaches include: RICE Therapy Rest, ice, compression, and elevation (RICE) help reduce swelling and alleviate pain