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If you're considering B12 supplementation, speak with your healthcare provider to determine if it's right for you

The primary safety consideration is ensuring proper dosing relative to body weight and metabolic baseline, not interaction risk between the two compounds
[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification

Finally, we review the numerous recent high-quality preclinical studies that investigated methods to restore NAD + levels to treat ageing-related diseases

It may or may not be the answer but the consequences of not trying it are to horrible to contemplate
