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Metformin , the first-line oral agent for type 2 diabetes recommended by NICE (NG28), is primarily associated with gastrointestinal side effects rather than headaches
Patients will often feel fuller after eating smaller portions and may see an improvement in their energy levels and metabolism

As assessed by baseline fundoscopic examination, 15% of the population had retinopathy

As of 2026, only Wegovy (semaglutide) has an oral tablet, launched January 2026

Available from: [2] Dutta P, Kumar Y, Babu AT, Giri Ravindran S, Salam A, Rai B, et al

microdose)
