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This dual inhibition effectively blocks the transdifferentiation and activation of quiescent hepatic stellate cells (HSCs) into collagen-secreting myofibroblasts, markedly decreasing deposition of fibrillar collagen type I (Col I) and -smooth muscle actin (-SMA), while also triggering cell cycle arrest in activated HSCsthereby halting fibrotic expansion

Possible side effects include nausea, headaches, and mild discomfort at the injection site when administered improperly

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