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Laboratory investigations using mammalian chondrocytes expanded in vitro show that the senolytic peptide selectively removes senescent cells while significantly reducing senescence-associated -galactosidase staining

Examines NNMT regulation in hepatic tissue and its relationship to fasting states and lipid metabolism, providing mechanistic context for NNMT inhibitor research

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Because reactive oxygen species (ROS) have been implicated as mediators of inflammatory bowel disease (IBD), the purpose of the present work was to determine the functional role of mucosal GSH in the trinitrobenzenesulfonic acid in 50% ethanol (TNBS+ethanol)-induced colitis in rats

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