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doi: 10.4172/2155-9929.1000364

In this review, we summarize the current understanding of molecular and cellular mechanisms involved in tumor angiogenesis, the molecular and functional heterogeneities of tumor vessels and emerging concepts for vascular targeting during cancer therapy

In conclusion, the overuse of FQs and the growing number of reports of chronic adverse reactions (ADRs), including potential FQAD, are the main reasons to avoid FQs when other safer alternatives are available

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BPC157 specifically bound FBXO22 with a dissociation constant KD of 1.0 10, which was significantly greater than that of the scrambled peptide control (KD = 2.6 10) (Fig