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Glutathione helps neutralize that damage before it builds up

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Science 124: 269270 Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB (2010) The hexosamine biosynthetic pathway couples growth factorinduced glutamine uptake to glucose metabolism

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Given the importance of ROS, including hydrogen peroxide, in many cellular events, we also discuss the consequences of excess or sustained GPx1 activity in biological systems

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