kinetic study on the reactions of platinum drugs with glutathione Glutathione-Mediated Conjugation Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation A cisplatin-based platinum(IV) prodrug containing
Description
Although BSO+L-PAM were not as active in the TX-MM-030h cell line (established at relapse after therapy with myeloablative L-PAM) as in other cell lines, BSO+L-PAM had a greater than additive effect and induced 3 logs of cell kill
Higher dose glutathione IVs may be administered more slowly, which can extend session length and affect overall cost
Younossi et al
Vi thnh phn Glutathione, sn phm h tr ci thin sc t da, mang li cm gic ti tn, u mu v rng r sau khi s dng
10.1189/jlb.1209811 182 McLeishK
Pediatr Nephrol 33:11651172
