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To reduce gelification risk: use adequate solvent volume (avoid high concentrations), mix gently, allow equilibration at room temperature, and apply slight warming if needed

Proc Natl Acad Sci USA 106: 1679916804, 2009

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NICE-recommended licensed options include semaglutide (Wegovy) for adults meeting specific BMI and comorbidity criteria under NICE TA875, and orlistat available on prescription or over the counter