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Furthermore, the decrease in SOD and CAT activity suggests that TMX may considerably deplete the endogenous antioxidant system in the metabolic degradation of superoxide radicals and H 2 O 2 due to increased oxidative stress (Kati et al

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Notably, pigmented C57BL/6-HGF animals also produced spontaneous melanomas (no ultraviolet), which were absent in genetically matched albino C57BL/6-c-HGF transgenic mice (Fig

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