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In human CECs (HCECs) exposed to phenylarsine oxide (PAO), a highly toxic trivalent arsenical, significant oxidative stress was reported by Kandhari et al., accompanied by ferroptotic cell death (115)

This creates a theoretical concern that copper peptides might accelerate tumor development in individuals with active cancer or dormant tumors

Thus, depending on the make up of the transcription factors bound to the ARE, opposite effects may occur

However, higher doses and longer durations of supplementation may potentially lead to increased glutathione levels in the body

H., Tishler, T

What to Expect After Glutathione Treatment