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Purity: Refer to batch-specific Certificate of Analysis (COA)

Check pH:Test your serum's pH with strips or a meter. Aim for 4.55.5. If it's too alkaline, add a tiny amount of citric acid dissolved in a few drops of water. If too acidic, add a minimal amount of sodium hydroxide solution. Retest after each adjustment

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Cell proliferation was assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetra-zolium bromide (MTT

In imiquimod-induced mouse models, betulin-loaded NLCs produced marked lesion improvement accompanied by reductions in systemic inflammatory cytokines such as TNF-, IL-6, and IL-17, along with a lowered spleen index, indicating that their therapeutic benefit extends beyond local skin improvement to systemic immunomodulation [123, 124]

10.1016/j.ygeno.2022.110519 83 PengY