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Even if these concerns are addressed, GBCA administration requires intravenous access, a requirement that places risks on patients and healthcare practitioners, as well as limiting its application in cases when contraindicated (Guo et al., 2018)

however, the use of hemoglobin chloride for stimulating kidney injury does not accurately mimic the features of open surgery

doi.org/10.1038/nature03000 Smart, N., et al

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