glutathione as nitric oxide carrier responsive release for enhanced photodynamic therapy by a porphyrinic MOF nanosystem The emerging roles of nitric

However, where more than one therapeutic approach was applied, such as an adjunctive immune modulator, intravesical injection, intravesical instillation with BTX or HA, or HA and CS, or changes in diet, more positive outcomes could be anticipated which could be demonstrated in the future by RCTs

W., Dworaczyk, D., Ganis, B., & Weiser, M

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Generally well tolerated in human studies

These classes instead include structures identified in cell or tissue cultures or in other species, structures predicted based on rule-based enzymatic derivatizations of known human metabolites, and structures predicted based on combinatorial enumeration (for instance, of lipid head groups and acyl/alkyl chains)

Three of the studies are clinical