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Description
"A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models"

During the process of aging, the expression of MMP increases in fibroblasts, whereas the expression of MMP inhibitors (TIMP) decreases

"To Settle Suit, Maker Agrees to Withdraw Growth Drug"

After 6 weeks, the gene-modified group exhibited improved toughness, maximal load to failure, and organized collagen bundles compared to controls (Zhang et al., 2021)

Supplementary Information Additional file 1: Supplementary figure S1

A Randomized Controlled Clinical Trial in Hemodialysis patients
