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The frequency of B12 Shots varies based on individual energy levels, health goals, and metabolic needs

Nutrients 12 , 3207 (2020)

On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

PubMed PMID: doi:10.1186/1476-069X-12-41