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Staege, M

Nivells baixos de glutati es relacionen amb una disminuci del metabolisme lipdic i, per tant, un increment en l'emmagatzematge de greixos en l'organisme

In the first step of the metabolic pathway, L-ornithine is converted to putrescine by ornithine decarboxylase (ODC1)

M2 macrophages are anti-inflammatory

reported that in U87 and U251 cells with increased iron uptake, the overexpression of transferrin receptor 2 (TFR2), a protein responsible for cellular iron uptake, is associated with increased susceptibility to ferroptosis (39)

Nonetheless, AAV-specific immune responses have been observed, which may induce potentially harmful inflammatory reactions and compromise the outcome of gene therapy [8]