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Emodin significantly mitigates cyclophosphamide-induced testicular toxicity in rats by improving sperm function and reproductive hormones levels, reversing oxidative stress and inflammation, and increasing testicular antioxidant enzymes, demonstrating its potential to counteract chemotherapy-related testicular damage [492]

Antioxidants have been proposed to improve the effects of antithyroid drugs in GH patients, as well as the remodeling of orbital tissues in patients with GO

However, a recent study questioned the role of IGF-I in cancer cachexia in the C26 tumor model

Mitochondria and Mitochondrial Cascades in Alzheimers Disease

J Neural Transmission 111:11911201 Michel TM et al (2007) Evidence for oxidative stress in the frontal cortex in patients with recurrent depressive disorder - a post-mortem study

Necroptosis in Development, Inflammation and Disease