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The increase in melanin production is what allows for sunless tanning

[PubMed: 24285566] 128

For example, it is easy to catastrophise or have a fear of re-injury that can slow down healing

(November 2013)

Timeline expectations: 48-72 hours (increased energy and reduced appetite), 1-2 weeks (initial weight loss 2-4 pounds), 4 weeks (noticeable body composition improvements), and 6 weeks (sustained metabolic enhancement and continued fat loss)

The latter would have important implication for AD because the amyloid precursor protein (APP) is continuously moved by axonal transport (26, 27) to serve many physiological functions (28)