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In this regard, studies have confirmed that Bax expression is upregulated in noise-exposed rats [81]

Although adverse effects are associated with this type of treatment, the therapeutic benefits are evident (Khler-Forsberg et al., 2023)

[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Slika, H

D.FaouziS.MaherJ

SOD3 knockout mice do not show any prominent phenotypic alteration in male reproduction, although the presence of SOD3 in the penis has been associated with increased erectile function in aged mice (95)

Neuroprotection and Neurodegenerative Disease The brain is particularly vulnerable to oxidative stress due to its high oxygen consumption rate (20% of total body O 2 ), abundance of peroxidation-susceptible polyunsaturated fatty acids, relatively low antioxidant enzyme expression compared to liver, and high iron content in specific regions (substantia nigra, striatum)