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Repetition of treatment For deficiencies we recommend once weekly for 4 weeks, followed by once a month until symptoms have improved

Kidney BA, Haines DM, Ellis JA, Burnham ML, Teifke JP, Czerwinski G, et al (2001b): Evaluation of formalin-fixed paraffin-embedded tissues from vaccine site-associated sarcomas of cats for papillomavirus DNA and antigen

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The liver stores the majority (approximately 50-60%) of the body's total B12 reserves (around 25 mg in healthy adults)

Symptoms of overmethylation can include: [23] Restless legs/pacing Hyperactivity High pain tolerance Histamine intolerance Sleep disorders Panic disorders Paranoia Insomnia Low libido ADHD Low motivation Depression Anxiety High levels of neurotransmitters (dopamine, norepinephrine, and serotonin) A high copper to zinc ratio Generally, undermethylation will result in symptoms more akin to depression and sluggishness, while overmethylation is usually linked to symptoms like hyperactivity and anxiety