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doi: 10.1212/WNL.30.7.772

Biogerontology, 2010

acutorostrata and the other sequenced mammalian genomes

10.1111/bjd.15015 Br

When iron is deficient, these processes are reversed, with the end result being a match between the levels of iron and PP 9, the two substrates for the final enzyme of heme biosynthesis, namely, ferrochelatase [FECH], thus minimizing excesses of toxic substrates in erythroblasts

This historical context is important because it reveals that coffee enemas emerged not from systematic medical research, but from early alternative medicine theories that predate our current understanding of human physiology and detoxification