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doi: 10.1038/s41746-023-00994-6 104
Mice were checked twice a week by a veterinarian responsible for animal welfare monitoring for signs of sufferance such as weight loss, decreased water and food consumption, poor hair coat, decreased activity levels accordingly to the guidelines for a correct laboratory practice and signs of poor quality of life
The single nucleotide polymorphism rs5400 in SLC2A2 in human CD8 + T cells reduces glucose uptake and inhibits CD8 + T cell proliferation [98]
Hagen K
Moreover, Scap deficiency does not impact T cell homeostasis
Neither is inherently better
