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Injection-site irritation can occur with any shot, and ingredient-specific reactions are possible

For IM injections, a 22 to 25 gauge needle is typically used

The vitamin can be stored in the liver for a long time, so it may take a few years for a deficiency to develop ( Summary Vitamin B12 is a water-soluble vitamin that plays an important role in brain function and red blood cell production

Apply a cold pack to the injection site before and after the injection to reduce pain

But for most purposes (like weekly maintenance injections), IM is the preferred route at home because its simpler (the vitamins absorb quickly from muscle into the bloodstream over a few hours)

Adequate intake (AI): AI is the average intake level taken by people who areconsidered Trusted Source PubMed Central Go to sourceto be healthy in studies